The TSPAN5 Polyclonal Antibody (PAC012962) is a valuable tool for researchers studying TSPAN5, a member of the tetraspanin family of proteins known to be involved in various cellular processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the TSPAN5 protein, this antibody allows for the detection and analysis of TSPAN5 expression in different cell types, making it ideal for studies in cell biology and cancer research.
TSPAN5 is recognized for its role in cell adhesion, migration, and signaling, making it a promising target for investigations into cancer metastasis and tumor progression. Its involvement in these processes highlights its potential as a therapeutic target for developing novel anti-cancer strategies. Understanding the mechanisms by which TSPAN5 functions can provide valuable insights into the development and progression of cancer, offering new avenues for targeted treatment approaches.
TSPAN5: is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provided by RefSeq, Jul 2008]Protein type: Motility/polarity/chemotaxis; Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 4q23Cellular Component: integral to plasma membrane; plasma membraneMolecular Function: enzyme bindingBiological Process: cell surface receptor linked signal transduction; positive regulation of Notch signaling pathway; protein maturation
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provided by RefSeq, Jul 2008]
