The TSPYL6 Polyclonal Antibody (PAC020780) is a valuable tool for researchers studying TSPYL6, a protein involved in cell growth regulation and cancer development. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blotting applications. By targeting the TSPYL6 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it ideal for investigations in oncology and cell biology.TSPYL6, also known as testis-specific Y-encoded-like protein 6, is a key player in the control of cell proliferation and differentiation, with implications for cancer progression and tumor growth.
Its role in signaling pathways related to cell cycle regulation and apoptosis makes it a promising target for research aimed at understanding and treating cancer. By uncovering the mechanisms by which TSPYL6 influences tumorigenesis, researchers can potentially identify new therapeutic strategies for combating cancer and other proliferative diseases.
Antibody Name:
TSPYL6 Antibody (PACO20780)
Antibody SKU:
PACO20780
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human TSPYL6
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO20780(TSPYL6 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using PACO20780(TSPYL6 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
TSPYL6 (Testis-specific Y-encoded-like protein 6) is a 410 amino acid, member of the nucleosome assembly protein (NAP) family. TSPYL6 is believed to be similar to Testis-specific Y-encoded protein 1 in form and function. The gene that encodes TSPYL6 is found on chromosome 2 which consists of 237 million bases encoding over 1,400 genes and making up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr m syndrome is due to mutations in the ALMS1 gene.
Synonyms:
TSPY-like 6
UniProt Protein Function:
TSPYL6: Belongs to the nucleosome assembly protein (NAP) family.Protein type: Unknown functionChromosomal Location of Human Ortholog: 2p16.2
