The TSSC1 Polyclonal Antibody (PACO05259) is a valuable tool for researchers studying TSSC1, a key player in cell proliferation and differentiation processes. This antibody, generated in rabbits, shows high specificity for human TSSC1 protein and is validated for use in Western blotting and immunohistochemistry.TSSC1, also known as Tumor Suppressor in Lung Cancer-1, is involved in the regulation of cell cycle and apoptosis, making it a promising target for cancer research. Its expression levels have been linked to various malignancies, making the antibody an essential tool for investigating TSSC1's role in tumorigenesis and potential therapeutic strategies.
By using the TSSC1 Polyclonal Antibody, researchers can gain insights into the mechanisms underlying cancer development and progression, paving the way for the development of novel treatment approaches targeting TSSC1 pathways. This antibody is a valuable addition to any laboratory conducting research on cancer biology and molecular oncology.
Antibody Name:
TSSC1 Antibody (PACO05259)
Antibody SKU:
PACO05259
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:10000, WB:1:500-1:2000
Species Reactivity:
Human, Mouse, Rat, Monkey
Immunogen:
Synthesized peptide derived from the C-terminal region of human TSSC1.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
TSSC1; Protein TSSC1; Tumor-suppressing STF cDNA 1 protein; Tumor-suppressing subchromosomal transferable fragment candidate gene 1 protein
UniProt Protein Function:
TSSC1: Chromosomal Location of Human Ortholog: 2p25.3
UniProt Protein Details:
NCBI Summary:
This gene has been reported in PMID 9403053 as one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alignment of this gene to genomic sequence data suggests that this gene resides on chromosome 2 rather than chromosome 11. [provided by RefSeq, Dec 2008]
