The TSSK6 Polyclonal Antibody (PAC005486) is a valuable tool for researchers studying TSSK6, a testis-specific serine/threonine-protein kinase involved in sperm development and function. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the TSSK6 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an excellent choice for studies in reproductive biology and fertility research.
TSSK6 is known to play a crucial role in spermatogenesis, where it regulates the process of sperm maturation and motility. Understanding the function of TSSK6 is essential for unraveling the mechanisms behind male fertility and potential therapeutic interventions for infertility issues. By targeting TSSK6 with this specific antibody, researchers can gain valuable insights into the molecular pathways involved in spermatogenesis and potential targets for novel reproductive treatments.
Antibody Name:
TSSK6 Antibody (PACO05486)
Antibody SKU:
PACO05486
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:40000, IHC:1:100-1:300
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthesized peptide derived from the Internal region of human TSSK 6.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
SSTK: a calmodulin-dependent kinase of the TSSK family. Protein type: Cancer Testis Antigen (CTA); Kinase, protein; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); Protein kinase, CAMK; CAMK group; TSSK familyChromosomal Location of Human Ortholog: 19p13.11Cellular Component: cytoplasm; nucleusMolecular Function: ATP binding; magnesium ion binding; protein binding; protein serine/threonine kinase activityBiological Process: protein amino acid phosphorylation; sperm chromatin condensation
UniProt Protein Details:
NCBI Summary:
This intronless gene encodes a member of the CAMK (calcium/calmodulin-dependent) serine/threonine protein kinase family. The encoded kinase has a broad expression pattern but is described as testis-specific due to effects on fertility. Male mice which lack the gene encoding a highly similar protein are sterile and have morphologically abnormal sperm. [provided by RefSeq, Jan 2012]
