The TUBA1C Polyclonal Antibody (PAC017334) is a valuable tool for researchers studying TUBA1C, a key protein component of microtubules essential for cell division and intracellular transport. This antibody, generated in rabbits, shows high specificity for human samples and has been validated for use in Western blot applications. By targeting the TUBA1C protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an ideal choice for studies in cell biology and cancer research.
TUBA1C plays a crucial role in maintaining cell structure and function, making it a promising target for research on diseases such as cancer and neurodegenerative disorders. Understanding the function and regulation of TUBA1C is vital for uncovering its role in disease development and progression. This antibody provides researchers with a reliable tool for investigating the biological pathways involving TUBA1C and exploring potential therapeutic interventions.
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO17334(TUBA1C Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200).
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-4: NIH/3T3, K562, A431 and hela cell, Primary antibody: PACO17334(TUBA1C Antibody) at dilution 1/300 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds.
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using PACO17334(TUBA1C Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200).
Background:
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the β chain and one at a non-exchangeable site on the α chain.
Synonyms:
tubulin, α 1c
UniProt Protein Function:
TUBA1C: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. Dimer of alpha and beta chains. Belongs to the tubulin family.Protein type: Cytoskeletal; Motility/polarity/chemotaxisChromosomal Location of Human Ortholog: 12q13.12Cellular Component: microtubule; nucleus; vesicleMolecular Function: protein binding; structural molecule activityBiological Process: cell division; cytoskeleton-dependent intracellular transport; microtubule-based process
