The Tubal3 Antibody (PAC030886) is a polyclonal antibody specifically designed for research involving Tubal3, a protein that plays a crucial role in DNA replication and cell division. The antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications, including Western blotting.Tubal3 is essential for the accurate separation of chromosomes during cell division, making it a key player in maintaining genomic stability and preventing the development of genetic abnormalities. Dysregulation of Tubal3 has been linked to various diseases, including cancer, making it a promising target for research aimed at understanding the molecular mechanisms underlying these conditions.
By targeting Tubal3 with this antibody, researchers can effectively detect and analyze the expression of Tubal3 in different cell types, providing valuable insights into its function and potential implications in disease development. This makes the Tubal3 Antibody a valuable tool for studies in molecular biology, cancer research, and genetics, offering new opportunities for breakthrough discoveries in the field.
Antibody Name:
TUBAL3 Antibody (PACO30886)
Antibody SKU:
PACO30886
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Tubulin α chain-like 3 protein (1-300AA)
Immunohistochemistry of paraffin-embedded human spleen tissue using PACO30886 at dilution of 1:100.
Background:
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the β chain and one at a non-exchangeable site on the α chain.
Synonyms:
Tubulin α chain-like 3, TUBAL3
UniProt Protein Function:
TUBAL3: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. Belongs to the tubulin family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: CytoskeletalChromosomal Location of Human Ortholog: 10p15.1Cellular Component: cytoplasm; microtubuleMolecular Function: GTP binding; GTPase activity; structural constituent of cytoskeletonBiological Process: 'de novo' posttranslational protein folding; cellular protein metabolic process; microtubule-based process; protein folding
