Description
Anti-TUBB2 Antibody (MACO0469)
The TUBB2 Monoclonal Antibody (MAC0469) is a powerful tool for researchers studying the TUBB2 protein, a key player in microtubule dynamics and cellular structure. This antibody, developed using a monoclonal approach, boasts high specificity and sensitivity in detecting TUBB2 in various experimental settings.TUBB2, a member of the tubulin superfamily, is essential for processes such as cell division, intracellular transport, and cell motility. Dysregulation of TUBB2 has been linked to neurodevelopmental disorders, cancer metastasis, and drug resistance mechanisms, making it a hot topic in molecular biology and pharmacology research.
With its ability to recognize TUBB2 in different cell types and tissues, the MAC0469 antibody is a valuable tool for investigating the role of TUBB2 in various biological processes. Whether you are studying cell migration, mitosis, or drug response mechanisms, this antibody is a reliable partner in your quest for new scientific insights.
| Product Name: | Anti-TUBB2 Antibody |
| Product Sku: | MACO0469 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IP |
| Recommended Dilutions: | WB:1:500-1:5000, IP:1:200-1:2000 |
| Species Reactivity: | Rat, Mouse, Human |
| Immunogen: | Recombinant Protein |
| Form: | Liquid |
| Storage Buffer: | Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Monoclonal |
| Isotype: | IgG1 |
| Conjugate: | Non-conjugated |
| Background: | Tubulin is the major constituent of microtubules. It exists as a heterodimer consiting of an alpha and a beta subunit. Class II beta tubulin is the major form of tubulin beta in neurons, although it is not neuronal specific. It is found in many other tissues including lung tissue and Schwann cells. |
| Synonyms: |
| UniProt Protein Function: | TUBB2C: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. Belongs to the tubulin family. |
| UniProt Protein Details: | Protein type:Cytoskeletal; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 9q34 Cellular Component: cytoskeleton; cytosol; microtubule; nucleus Molecular Function:double-stranded RNA binding; MHC class I protein binding Biological Process: cell motility; G2/M transition of mitotic cell cycle |
| UniProt Code: | P68371 |
| NCBI GenInfo Identifier: | 55977480 |
| NCBI Gene ID: | 10383 |
| NCBI Accession: | P68371.1 |
| UniProt Secondary Accession: | P68371,P05217, A2BFA2, |
| UniProt Related Accession: | P68371 |
| Molecular Weight: | 49,831 Da |
| NCBI Full Name: | Tubulin beta-4B chain |
| NCBI Synonym Full Names: | tubulin beta 4B class IVb |
| NCBI Official Symbol: | TUBB4B |
| NCBI Official Synonym Symbols: | Beta2; TUBB2; TUBB2C |
| NCBI Protein Information: | tubulin beta-4B chain |
| UniProt Protein Name: | Tubulin beta-4B chain |
| UniProt Synonym Protein Names: | Tubulin beta-2 chain; Tubulin beta-2C chain |
| Protein Family: | Tubulin |
| UniProt Gene Name: | TUBB4B |
| UniProt Entry Name: | TBB4B_HUMAN |
