Description
TUBB2A Antibody (PACO00107)
The TUBB2A Polyclonal Antibody (PACO00107) is a valuable tool for researchers studying TUBB2A, a key protein involved in microtubule formation and cell division. This antibody, produced in rabbits, exhibits high specificity and reactivity with human samples, making it an ideal choice for experiments such as Western blotting.TUBB2A is a crucial component of the cytoskeleton and is essential for proper cellular organization and movement. Dysregulation of TUBB2A has been implicated in various diseases, including cancer and neurological disorders.
By targeting TUBB2A with this antibody, researchers can investigate its role in disease development and progression, paving the way for potential therapeutic interventions.Overall, the TUBB2A Polyclonal Antibody offers high-quality performance and reliability for studies focused on understanding the function and regulation of TUBB2A in a variety of biological and pathological processes.
| Antibody Name: | TUBB2A Antibody |
| Antibody SKU: | PACO00107 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | synthetic Peptide |
| Form: | Liquid |
| Storage Buffer: | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
| Purification Method: | Affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | Tubulin beta-2A chain |
| UniProt Protein Function: | TUBB2A: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. Belongs to the tubulin family. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Cytoskeletal Chromosomal Location of Human Ortholog: 6p25 Cellular Component: cytoplasm; microtubule; nucleus Molecular Function:GTP binding; GTPase activity; protein binding; structural constituent of cytoskeleton Biological Process: 'de novo' posttranslational protein folding; cellular protein metabolic process; microtubule-based process; protein folding Disease: Cortical Dysplasia, Complex, With Other Brain Malformations 5 |
| NCBI Summary: | Microtubules, key participants in processes such as mitosis and intracellular transport, are composed of heterodimers of alpha- and beta-tubulins. The protein encoded by this gene is a beta-tubulin. Defects in this gene are associated with complex cortical dysplasia with other brain malformations-5. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2015] |
| UniProt Code: | Q13885 |
| NCBI GenInfo Identifier: | 74762137 |
| NCBI Gene ID: | 7280 |
| NCBI Accession: | Q13885.1 |
| UniProt Secondary Accession: | Q13885,Q6FGZ8, Q8IWR2, |
| UniProt Related Accession: | Q13885 |
| Molecular Weight: | 49,907 Da |
| NCBI Full Name: | Tubulin beta-2A chain |
| NCBI Synonym Full Names: | tubulin beta 2A class IIa |
| NCBI Official Symbol: | TUBB2AÂ Â |
| NCBI Official Synonym Symbols: | TUBB; TUBB2; CDCBM5Â Â |
| NCBI Protein Information: | tubulin beta-2A chain |
| UniProt Protein Name: | Tubulin beta-2A chain |
| UniProt Synonym Protein Names: | Tubulin beta class IIa |
| Protein Family: | Tubulin |
| UniProt Gene Name: | TUBB2AÂ Â |
| UniProt Entry Name: | TBB2A_HUMAN |
