The TUSC1 Polyclonal Antibody (PAC020792) is a valuable tool for researchers studying TUSC1, a potential tumor suppressor gene implicated in cancer development and progression. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications, enabling accurate detection of TUSC1 protein levels in various cell types.TUSC1, also known as tumor suppressor candidate 1, is believed to play a role in regulating cell growth and proliferation, making it a promising target for cancer research. By targeting TUSC1, researchers may gain insights into the mechanisms underlying tumor formation and potentially identify new therapeutic strategies for combating cancer.
With its high reactivity and specificity, the TUSC1 Polyclonal Antibody is an essential tool for investigating the functions of TUSC1 in cancer biology and beyond. By providing reliable and accurate detection of TUSC1 protein expression, this antibody facilitates in-depth studies into the potential roles of TUSC1 in tumorigenesis and may ultimately contribute to the development of novel cancer therapies.
Antibody Name:
TUSC1 Antibody (PACO20792)
Antibody SKU:
PACO20792
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human TUSC1
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using PACO20792(TUSC1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20792(TUSC1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
This gene is located within the region of chromosome 9p that harbors tumor suppressor genes critical in carcinogenesis. It is an intronless gene which is downregulated in non-small-cell lung cancer and small-cell lung cancer cell lines, suggesting that it may play a role in lung tumorigenesis.
Synonyms:
tumor suppressor candidate 1
UniProt Protein Function:
TUSC1:
UniProt Protein Details:
Chromosomal Location of Human Ortholog: 9p21.2
NCBI Summary:
This gene is located within the region of chromosome 9p that harbors tumor suppressor genes critical in carcinogenesis. It is an intronless gene which is downregulated in non-small-cell lung cancer and small-cell lung cancer cell lines, suggesting that it may play a role in lung tumorigenesis. [provided by RefSeq, Jul 2008]
