The TUSC5 Antibody (PAC020795) is a polyclonal antibody designed for research involving the TUSC5 protein, which is implicated in various cellular processes related to metabolism and energy homeostasis. Raised in rabbits, this antibody is highly reactive with human samples and has been validated for use in Western blot applications. It specifically binds to the TUSC5 protein, allowing for detection and analysis in a wide range of cell types.TUSC5, also known as Tumor Suppressor Candidate 5, is a significant player in metabolic functions, particularly in the regulation of glucose and lipid metabolism.
Its role in cellular energy balance and potential involvement in diseases such as obesity and diabetes make it a promising target for research in metabolic disorders. Understanding the functions and mechanisms of TUSC5 could lead to novel therapeutic strategies for managing metabolic diseases and improving overall health.
Antibody Name:
TUSC5 Antibody (PACO20795)
Antibody SKU:
PACO20795
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:30-1:150
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthetic peptide of human TUSC5
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO20795(TUSC5 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
TUSC5 (tumor suppressor candidate 5), also known as protein located at seventeen-p-thirteen point three 1, LOST1 or IFITMD3 (interferon-induced transmembrane domain-containing protein D3), is a 177 amino acid, multi-pass membrane protein that belongs to the CD225 family. Thought to play a role in fat metabolism, TUSC5 is highly expressed in mammary gland, heart, smooth muscle, skeletal muscle and stomach, with lower levels found in lung and brain.
Synonyms:
tumor suppressor candidate 5
UniProt Protein Function:
TUSC5: May be involved in fat metabolism. Belongs to the CD225/Dispanin family.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 17p13.3
Dispanin subfamily B member 1; DSPB1; Interferon-induced transmembrane domain-containing protein D3; Protein located at seventeen-p-thirteen point three 1
