The TXNDC11 Polyclonal Antibody (PAC017346) is a valuable tool for researchers studying TXNDC11, a protein involved in redox regulation and cell signaling pathways. This antibody, generated in rabbits, shows high specificity towards human samples and is validated for use in Western blot applications. By targeting the TXNDC11 protein, this antibody allows for accurate detection and analysis in various cell types, making it well-suited for investigations in molecular biology and cellular physiology.
TXNDC11, also known as thioredoxin domain-containing protein 11, is essential for maintaining cellular redox balance and regulating protein folding processes. Its role in redox signaling cascades makes it a promising target for research on oxidative stress-related diseases, neurodegenerative disorders, and cancer. Understanding the functions of TXNDC11 is crucial for developing targeted therapies that modulate redox pathways and enhance cellular resilience in disease states.
Antibody Name:
TXNDC11 Antibody (PACO17346)
Antibody SKU:
PACO17346
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:30-1:150
Species Reactivity:
Human
Immunogen:
Fusion protein of human TXNDC11
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using PACO17346(TXNDC11 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO17346(TXNDC11 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200).
Background:
May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H2O2generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H2O2 generation.
Synonyms:
thioredoxin domain containing 11
UniProt Protein Function:
May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H2O2 generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H2O2 generation.
