The Uhrf2 Antibody (CAB2344) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically targeting the UHRF2 protein, researchers can detect and analyze its expression in various cell types, making it ideal for studies in cancer biology, epigenetics, and cell cycle regulation.UHRF2, a member of the UHRF protein family, plays a critical role in maintaining genome stability and epigenetic marks through its interactions with DNA methyltransferases and histone modifying enzymes.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
Uhrf2 Antibody
SKU:
CAB2344
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
Nirf, 2310065A22Rik, D130071B19Rik, Uhrf2
Positive Sample:
Mouse thymus
Cellular Localization:
Nucleus.
Calculated MW:
90kDa
Observed MW:
95kDa
Enables histone binding activity. Predicted to be involved in several processes, including maintenance of DNA methylation; protein autoubiquitination; and regulation of cell cycle. Located in heterochromatin and nucleus. Is expressed in several structures, including central nervous system; ear; early conceptus; female reproductive system; and urinary system. Orthologous to human UHRF2 (ubiquitin like with PHD and ring finger domains 2).
Purification Method
Affinity purification
Gene ID
109113
RRID
AB_2764305
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from Mouse thymus, using Uhrf2 Rabbit pAb (CAB2344) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.