The UCN2 Antibody (CAB6485) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, specifically binds to Urocortin-2 in human samples and is validated for use in Western blotting applications.Urocortin-2 is known for its role in modulating cardiovascular function, energy metabolism, and stress response, making it a key target for research in cardiology, endocrinology, and neuroscience. By using this antibody, researchers can accurately detect and analyze the expression of Urocortin-2 in various cell types, shedding light on its physiological functions and potential therapeutic applications.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
UCN2 Antibody
SKU:
CAB6485
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
UR, SRP, URP, UCNI, UCN-II, UCN2
Positive Sample:
Rat skin
Cellular Localization:
Secreted.
Calculated MW:
12kDa
Observed MW:
12kDa
This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II.
Purification Method
Affinity purification
Gene ID
90226
RRID
AB_2767085
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from rat skin, using UCN2 Rabbit pAb (CAB6485) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
