Description
USP45 Antibody (PACO13137)
The USP45 Polyclonal Antibody (PAC013137) is a valuable tool for researchers studying USP45, a protein involved in cellular homeostasis and signaling pathways. This antibody, produced in rabbits, boasts high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the USP45 protein, this antibody allows for the detection and analysis of USP45 in a variety of cell types, making it ideal for studies in molecular biology and cell signaling research.USP45, a deubiquitinating enzyme, plays a crucial role in maintaining the balance of proteins in cells by regulating the ubiquitin-proteasome system.
Dysregulation of USP45 has been linked to various diseases, including cancer, neurodegenerative disorders, and inflammatory conditions. Researchers investigating USP45 aim to further understand its function and potential as a therapeutic target for these diseases.By utilizing the USP45 Polyclonal Antibody, researchers can gain valuable insights into the role of USP45 in cellular processes and disease pathways, ultimately paving the way for potential advancements in the development of targeted therapies.
| Antibody Name: | USP45 Antibody (PACO13137) |
| Antibody SKU: | PACO13137 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human USP45 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | ubiquitin specific peptidase 45;USP45;MGC14793 ; |
| UniProt Protein Function: | USP45: Belongs to the peptidase C19 family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 3.4.19.12; Ubiquitin-specific protease; Protease; Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 6q16.2 Cellular Component: cytoplasm; nucleoplasm; nucleus Molecular Function:ubiquitin-specific protease activity Biological Process: DNA repair; protein deubiquitination |
| UniProt Code: | Q70EL2 |
| NCBI GenInfo Identifier: | 296453002 |
| NCBI Gene ID: | 85015 |
| NCBI Accession: | Q70EL2.3 |
| UniProt Secondary Accession: | Q70EL2,Q5T062, Q86T44, Q86TC0, Q9BRU1, B2RXG0, |
| UniProt Related Accession: | Q70EL2 |
| Molecular Weight: | 55,812 Da |
| NCBI Full Name: | Ubiquitin carboxyl-terminal hydrolase 45 |
| NCBI Synonym Full Names: | ubiquitin specific peptidase 45 |
| NCBI Official Symbol: | USP45Â Â |
| NCBI Protein Information: | ubiquitin carboxyl-terminal hydrolase 45 |
| UniProt Protein Name: | Ubiquitin carboxyl-terminal hydrolase 45 |
| UniProt Synonym Protein Names: | Deubiquitinating enzyme 45; Ubiquitin thioesterase 45; Ubiquitin-specific-processing protease 45 |
| Protein Family: | Ubiquitin carboxyl-terminal hydrolase |
| UniProt Gene Name: | USP45Â Â |
| UniProt Entry Name: | UBP45_HUMAN |
