The UTS2R Polyclonal Antibody (CAB2959) is a valuable tool for researchers studying the UTS2R protein, a G-protein coupled receptor involved in regulating blood pressure and cardiovascular function. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the UTS2R protein, this antibody enables the detection and analysis of UTS2R expression in various cell types, making it ideal for studies in cardiovascular biology and hypertension research.UTS2R, also known as urotensin II receptor, is a key player in the urotensin system, which is involved in various physiological processes including vascular tone regulation and cardiovascular homeostasis.
Dysregulation of the UTS2R pathway has been linked to cardiovascular diseases such as hypertension, heart failure, and atherosclerosis. Investigating the role of UTS2R with the help of this antibody can provide valuable insights into the molecular mechanisms underlying these conditions and may lead to the development of novel therapeutic strategies targeting the UTS2R pathway.
Product Name:
UTS2R Rabbit Polyclonal Antibody
SKU:
CAB2959
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 280-389 of human UTS2R (NP_061822.1).
Sequence:
LAQY HQAP LAPR TARI VNYL TTCL TYGN SCAN PFLY TLLT RNYR DHLR GRVR GPGS GGGR GPVP SLQP RARF QRCS GRSL SSCS PQPT DSLV LAPA APAR PAPE GPRA PA
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:2000
Synonyms:
UTR; UTR2; GPR14; UR-2-R; UTS2R
Positive Sample:
HeLa,Mouse brain,Mouse heart,Rat brain
Conjugate:
Unconjugated
Cellular Localization:
Cell membrane, Multi-pass membrane protein.
Calculated MW:
42kDa
Observed MW:
42kDa
Predicted to enable urotensin II receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane.
Purification Method:
Affinity purification
Gene ID:
2837
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using UTS2R antibody (CAB2959) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
