The Vasohibin-1 Polyclonal Antibody (CAB6148) is a powerful tool for researchers studying Vasohibin-1, a protein with important roles in angiogenesis and tumor progression. This antibody, generated in rabbits, has high reactivity with human samples and has been validated for use in various research applications, including Western blotting.Vasohibin-1 is a known regulator of blood vessel formation and has been implicated in promoting tumor growth and metastasis. By targeting Vasohibin-1, researchers can gain insights into the mechanisms underlying angiogenesis and cancer progression.
This antibody specifically binds to Vasohibin-1, allowing for the detection and analysis of this protein in different cell types and tissues.The unique properties of the Vasohibin-1 Polyclonal Antibody make it an essential tool for studies in oncology and vascular biology. Understanding the functions of Vasohibin-1 may lead to the development of novel therapeutic strategies for cancer treatment and intervention in angiogenesis-related disorders.
Product Name:
VASH1 Rabbit Polyclonal Antibody
SKU:
CAB6148
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-365 of human VASH1 (NP_055724.1).
Enables actin binding activity and metallocarboxypeptidase activity. Involved in negative regulation of angiogenesis; negative regulation of blood vessel endothelial cell migration; and proteolysis. Acts upstream of or within several processes, including negative regulation of endothelial cell migration; negative regulation of endothelial cell proliferation; and negative regulation of lymphangiogenesis. Located in apical part of cell; endoplasmic reticulum; and extracellular space. Implicated in liver cirrhosis and portal hypertension. Biomarker of liver cirrhosis.
Purification Method:
Affinity purification
Gene ID:
22846
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using VASH1 antibody (CAB6148) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
