Description
VOPP1 Antibody (PACO31708)
The VOPP1 Polyclonal Antibody (PACO31708) is a valuable tool for researchers studying VOPP1, a protein involved in cell proliferation and cancer development. This antibody, generated in rabbits, exhibits high specificity and sensitivity in detecting VOPP1 in human samples, making it suitable for use in Western blot applications. By targeting the VOPP1 protein, this antibody enables researchers to investigate its role in various cellular processes, particularly in the context of cancer research.VOPP1, also known as VOPP1 Oncogene, has been shown to play a crucial role in promoting cell growth and tumor progression.
Its overexpression has been linked to various types of cancer, highlighting its potential as a therapeutic target. By elucidating the function of VOPP1, researchers can gain insights into the mechanisms underlying tumorigenesis and potentially develop novel anti-cancer strategies targeting this protein. The VOPP1 Polyclonal Antibody is an essential tool for advancing our understanding of VOPP1 biology and its implications in cancer biology.
| Antibody Name: | VOPP1 Antibody (PACO31708) |
| Antibody SKU: | PACO31708 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Vesicular, overexpressed in cancer, prosurvival protein 1 protein (23-172AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: VOPP1 antibody at 2µg/ml Lane 1: EC109 whole cell lysate Lane 2: 293T whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/15000 dilution Predicted band size: 20, 19, 18 kDa Observed band size: 50 kDa . |
| Background: | Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed. |
| Synonyms: | Vesicular, overexpressed in cancer, prosurvival protein 1 (EGFR-coamplified and overexpressed protein) (ECop) (Glioblastoma-amplified secreted protein) (Putative NF-kappa-B-activating protein 055N), VOPP1, ECOP GASP |
| UniProt Protein Function: | ECOP: Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed. Belongs to the VOPP1/ECOP family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 7p11.2Cellular Component: cytoplasmic vesicle membrane; endosomeMolecular Function: signal transducer activity |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q96AW1 |
| NCBI GenInfo Identifier: | 74760714 |
| NCBI Gene ID: | 81552 |
| NCBI Accession: | Q96AW1.1 |
| UniProt Secondary Accession: | Q96AW1,Q6FIE3, Q8NBN8, Q96RE5, Q9H0W4, B0AZU1, B2RAT4 B3KS72, C9JWR3 |
| UniProt Related Accession: | Q96AW1 |
| Molecular Weight: | 17,381 Da |
| NCBI Full Name: | Vesicular, overexpressed in cancer, prosurvival protein 1 |
| NCBI Synonym Full Names: | vesicular, overexpressed in cancer, prosurvival protein 1 |
| NCBI Official Symbol: | VOPP1Â Â |
| NCBI Official Synonym Symbols: | ECOP; GASPÂ Â |
| NCBI Protein Information: | vesicular, overexpressed in cancer, prosurvival protein 1 |
| UniProt Protein Name: | Vesicular, overexpressed in cancer, prosurvival protein 1 |
| UniProt Synonym Protein Names: | EGFR-coamplified and overexpressed protein; ECop; Glioblastoma-amplified secreted protein; Putative NF-kappa-B-activating protein 055N |
| Protein Family: | Vesicular, overexpressed in cancer, prosurvival protein |
| UniProt Gene Name: | VOPP1Â Â |
| UniProt Entry Name: | VOPP1_HUMAN |
