The VSIG10 Polyclonal Antibody (PAC020859) is a valuable tool for researchers studying the VSIG10 protein, a member of the V-set and immunoglobulin domain-containing (VSIG) protein family. This antibody, produced in rabbits, has high reactivity with human samples and is suitable for use in Western blot applications. By binding specifically to the VSIG10 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in immunology and cancer research.
VSIG10 is known for its role in immune regulation and has been implicated in processes such as T cell activation and peripheral tolerance. Its involvement in immune function suggests its potential as a therapeutic target for diseases involving dysregulated immune responses, such as autoimmune disorders and cancer. By understanding the function and expression of VSIG10, researchers can uncover insights that may lead to the development of novel immune-modulating therapies.
Antibody Name:
VSIG10 Antibody (PACO20859)
Antibody SKU:
PACO20859
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:30-1:150
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human VSIG10
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO20859(VSIG10 Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20859(VSIG10 Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fc receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3. The LOC147645 gene product has been provisionally designated LOC147645 pending further characterization.
