Description
WBSCR17 Antibody (PACO13222)
The Wbscr17 Polyclonal Antibody (PAC013222) is a valuable tool for researchers studying the Wbscr17 protein, which is involved in regulating cellular processes and gene expression. This antibody, generated in rabbits, demonstrates high specificity for human samples and is suitable for Western blot applications. By targeting the Wbscr17 protein, this antibody enables researchers to investigate its function and expression levels in various cell types, making it a versatile tool for studies in molecular biology and genetics.Wbscr17, also known as a transcriptional coactivator, plays a crucial role in modulating gene expression and cellular pathways.
Its involvement in transcriptional regulation makes it a key player in processes like cell differentiation and development. Understanding the function of Wbscr17 is essential for unraveling its contributions to diseases such as cancer, developmental disorders, and metabolic conditions. By utilizing the Wbscr17 Polyclonal Antibody, researchers can uncover new insights into the mechanisms underlying these diseases and potentially identify novel therapeutic targets.
| Antibody Name: | WBSCR17 Antibody (PACO13222) |
| Antibody SKU: | PACO13222 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human WBSCR17 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | Williams-Beuren syndrome chromosome region 17;WBSCR17;DKFZp434I2216;DKFZp761D2324;GALNT16;GALNT20;GALNTL3 ; |
| UniProt Protein Function: | WBSCR17: May catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. WBSCR17 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. |
| UniProt Protein Details: | Protein type:EC 2.4.1.41; Glycan Metabolism - O-glycan biosynthesis; Transferase; Membrane protein, integral Chromosomal Location of Human Ortholog: 7q11.23 Cellular Component: Golgi membrane; integral to membrane Molecular Function:polypeptide N-acetylgalactosaminyltransferase activity; metal ion binding; carbohydrate binding Biological Process: protein amino acid glycosylation |
| NCBI Summary: | This gene encodes an N-acetylgalactosaminyltransferase. This gene is located centromeric to the common deleted region in Williams-Beuren syndrome (WBS), a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. This protein may play a role in membrane trafficking. [provided by RefSeq, Jan 2013] |
| UniProt Code: | Q6IS24 |
| NCBI GenInfo Identifier: | 51315852 |
| NCBI Gene ID: | 64409 |
| NCBI Accession: | Q6IS24.2 |
| UniProt Secondary Accession: | Q6IS24,Q8NFV9, Q9NTA8, |
| UniProt Related Accession: | Q6IS24 |
| Molecular Weight: | 598 |
| NCBI Full Name: | Putative polypeptide N-acetylgalactosaminyltransferase-like protein 3 |
| NCBI Synonym Full Names: | Williams-Beuren syndrome chromosome region 17 |
| NCBI Official Symbol: | WBSCR17Â Â |
| NCBI Official Synonym Symbols: | GALNT16; GALNT20; GALNTL3; GALNACT17; GalNAc-T5LÂ Â |
| NCBI Protein Information: | putative polypeptide N-acetylgalactosaminyltransferase-like protein 3; galNAc-T-like protein 3; pp-GalNAc-transferase 20; pp-GaNTase-like protein 3; polypeptide GalNAc transferase 3; polypeptide GalNAc transferase-like protein 3; polypeptide N-acetylgalactosaminyltransferase-like 3; polypeptide N-acetylgalactosaminyltransferase WBSCR17; williams-Beuren syndrome chromosomal region 17 protein; protein-UDP acetylgalactosaminyltransferase-like protein 3; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like 3; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 3; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16 |
| UniProt Protein Name: | Putative polypeptide N-acetylgalactosaminyltransferase-like protein 3 |
| UniProt Synonym Protein Names: | Polypeptide GalNAc transferase-like protein 3; GalNAc-T-like protein 3; pp-GaNTase-like protein 3; Protein-UDP acetylgalactosaminyltransferase-like protein 3; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 3; Williams-Beuren syndrome chromosomal region 17 protein |
| Protein Family: | Putative polypeptide N-acetylgalactosaminyltransferase-like protein |
| UniProt Gene Name: | WBSCR17Â Â |
| UniProt Entry Name: | GLTL3_HUMAN |
