The WEE1 Monoclonal Antibody (CAB22275) is a high-quality antibody developed for reliable detection and analysis of target proteins. This monoclonal antibody, produced in mice, is highly specific for human samples and has been validated for use in a variety of applications, including Western blotting.Wee1 is a key protein involved in regulating the cell cycle by inhibiting the activity of cyclin-dependent kinases. Dysregulation of Wee1 has been linked to various diseases, including cancer, making it an important target for research in oncology. By utilizing the Wee1 Monoclonal Antibody, researchers can detect and analyze the expression of Wee1 in different cell types, providing valuable insights into its role in cell cycle control and potential therapeutic targeting.
This antibody is validated for use in IHC-P, ELISA applications and has demonstrated reactivity against Mouse samples.
Product Name:
WEE1 Monoclonal Antibody
SKU:
CAB22275
Size:
20μL, 100μL
Reactivity:
Mouse
Clone Number:
ARC57004
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
WEE1A, WEE1hu, WEE1
Cellular Localization:
Cytoplasm, Nucleolus, Nucleoplasm, Nucleus.
Calculated MW:
72kDa
Observed MW:
Refertofigures
This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.
Purification Method
Affinity purification
Gene ID
7465
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,0.05% BSA,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded Mouse testis tissue using WEE1 Rabbit mAb (CAB22275) at a dilution of 1:1000 (40x lens). High pressure antigen retrieval performed with 0.01M Tris-EDTA Buffer (pH 9.0) prior to IHC staining.
Immunohistochemistry analysis of paraffin-embedded Mouse spleen tissue using WEE1 Rabbit mAb (CAB22275) at a dilution of 1:1000 (40x lens). High pressure antigen retrieval performed with 0.01M Tris-EDTA Buffer (pH 9.0) prior to IHC staining.
