The WEE2 Polyclonal Antibody (PACO04478) is a valuable tool for researchers studying the WEE2 protein, a key regulator of cell cycle progression. This antibody, produced in rabbits, is highly specific to human samples and is suitable for use in Western blot applications. By binding to the WEE2 protein, this antibody allows for the detection and analysis of WEE2 expression in a variety of cell types.WEE2 is involved in the control of cell division and has been implicated in various cellular processes, including DNA replication and cell growth. Dysregulation of WEE2 has been linked to abnormal cell proliferation and may contribute to the development of cancer.
Therefore, studying the role of WEE2 in cell cycle regulation is essential for understanding the mechanisms underlying tumorigenesis and potential therapeutic interventions.Overall, the WEE2 Polyclonal Antibody is a valuable tool for researchers interested in exploring the functions of WEE2 in cell biology and cancer research. Its high specificity and reliability make it a trusted reagent for investigating the role of WEE2 in cellular processes and disease development.
Antibody Name:
WEE2 Antibody
Antibody SKU:
PACO04478
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human Wee 2.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
WEE2; WEE1B; Wee1-like protein kinase 2; Wee1-like protein kinase 1B; Wee1B kinase
UniProt Protein Function:
WEE1B: a protein kinase of the WEE family expressed only in oocytes. Downregulation by RNAi causes a leaky meiotic arrest. The inhibitory effects of the kinase are enhanced when Ser15 is phosphorylated. Appears to be a key MPF inhibitory kinase in mouse oocytes and is required for maintaining meiotic arrest.Protein type: Protein kinase, Other; EC 2.7.10.2; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Other group; WEE family; WEE1 subfamilyChromosomal Location of Human Ortholog: 7q32Cellular Component: nucleoplasm; cytoplasmMolecular Function: protein serine/threonine kinase activity; magnesium ion binding; non-membrane spanning protein tyrosine kinase activity; ATP bindingBiological Process: mitosis; peptidyl-tyrosine phosphorylation; female pronucleus formation; negative regulation of cyclin-dependent protein kinase activity; female meiosis
