The WNK2 Antibody (PAC020885) is a valuable tool for researchers studying WNK2, a protein kinase involved in various cellular processes, including ion transport and blood pressure regulation. This polyclonal antibody is produced in rabbits and is highly specific for human samples, making it ideal for Western blot applications. By binding to the WNK2 protein, researchers can effectively detect and analyze its expression in different cell types, furthering our understanding of its role in physiology and disease.
WNK2, also known as With No lysine (K), is a member of the WNK (With No lysine Kinase) family, which has been implicated in diseases like hypertension and kidney disorders. The antibody's ability to target WNK2 allows researchers to investigate its function in these conditions and potentially identify new therapeutic targets. By unraveling the molecular mechanisms involving WNK2, we can advance our knowledge of critical pathways and develop novel interventions for related diseases.
Gel: 6%SDS-PAGE,Lysate: 40 µg,Lane 1-2: MCF7 cells, Hela cells,Primary antibody: PACO20885(WNK2 Antibody) at dilution 1/200 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 10 minutes.
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20885(WNK2 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
The protein encoded by this gene is a cytoplasmic serine-threonine kinase that belongs to the protein kinase superfamily. The protein plays an important role in the regulation of electrolyte homeostasis, cell signaling survival, and proliferation. Alternative splicing results in multiple transcript variants.
