The XKR3 Polyclonal Antibody (PAC020936) is a valuable tool for research involving XKR3, a member of the XKR family of proteins implicated in various cellular functions. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the XKR3 protein, researchers can accurately detect and analyze its expression in different cell types, making it an ideal tool for studies in cell biology and genetics.XKR3 is known to play a role in cell homeostasis, membrane transport, and apoptosis regulation, making it a promising target for research into diseases such as cancer, neurodegenerative disorders, and developmental abnormalities.
By understanding the function of XKR3, researchers can uncover new insights into cellular processes and potentially develop novel therapeutic approaches for a range of conditions.Overall, the XKR3 Polyclonal Antibody (PAC020936) is a valuable resource for researchers looking to study the role of XKR3 in various biological processes and diseases, providing reliable and accurate results for their experiments.
Gel: 8%SDS-PAGE, Lysate: 40 µg, Lane 1-2: Human thyroid cancer and normal stomach tissue, Primary antibody: PACO20936(XKR3 Antibody) at dilution 1/200 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes.
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20936(XKR3 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
XKRX (MIM 300684) and XKR3 are homologs of the Kell blood group precursor XK (MIM 314850), which is a putative membrane transporter and a component of the XK/Kell complex of the Kell blood group system (Calenda et al., 2006 [PubMed 16431037]).
Synonyms:
XK, Kell blood group complex subunit-related family, member 3
UniProt Protein Function:
XKR3: Belongs to the XK familyProtein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 22q11.1
UniProt Protein Details:
NCBI Summary:
XKRX (MIM 300684) and XKR3 are homologs of the Kell blood group precursor XK (MIM 314850), which is a putative membrane transporter and a component of the XK/Kell complex of the Kell blood group system (Calenda et al., 2006 [PubMed 16431037]).[supplied by OMIM, Mar 2008]
