The XKR4 Antibody (PAC020939) is a highly specific tool for researchers studying XKR4, a key protein involved in various cellular processes such as apoptosis and phospholipid scrambling. This polyclonal antibody, developed against XKR4, has been raised in rabbits and is suitable for use in Western blot applications. It shows high reactivity with human samples, making it an excellent choice for studies focusing on cell biology and molecular mechanisms.XKR4 is a member of the XKR family of proteins, known for their role in mediating cell death and membrane dynamics. The antibody binds specifically to XKR4, enabling precise detection and analysis in different cell types.
This makes it a valuable resource for researchers studying cell signaling pathways, membrane biology, and apoptosis mechanisms.The XKR4 Antibody is an essential tool for investigations into the function and regulation of XKR4 in various biological processes. Its application in research on cell death, membrane dynamics, and disease mechanisms makes it a versatile and valuable addition to any laboratory conducting studies in cell biology, apoptosis, and related fields.
Antibody Name:
XKR4 Antibody (PACO20939)
Antibody SKU:
PACO20939
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:20-1:100
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthetic peptide of human XKR4
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20939(XKR4 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO20939(XKR4 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
XKR4 (XK-related protein 4) is a 650 amino acid, multi-pass membrane protein that likely is a component of the XK/Kell complex of the Kell blood group system. The gene encoding XKR4 maps to human chromosome 8, which is made up of nearly 146 million bases and encodes about 800 genes. Single nucleotide polymorphisms (SNPs) of the XKR4 gene are associated with iloperidone efficacy, a antipsychotic drug that is used to treat schizophrenic patients.
Synonyms:
XK, Kell blood group complex subunit-related family, member 4
UniProt Protein Function:
XKR4: Belongs to the XK family.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 8q12.1Cellular Component: membrane
