The XKR4 Antibody (PAC020940) is a polyclonal antibody designed for research involving the XKR4 protein, a member of the X-Kell family. This antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications such as Western blot and immunohistochemistry.XKR4 is a transmembrane protein that has been implicated in various cellular processes, including apoptosis and cell adhesion. Its role in these processes makes it a valuable target for research in areas such as cancer biology, developmental biology, and cell signaling pathways.
By using the XKR4 Antibody, researchers can confidently detect and analyze XKR4 protein levels in different cell types and tissues, allowing for a better understanding of its function and potential implications in disease mechanisms. This antibody is an essential tool for studying the physiological functions of XKR4 and its involvement in various cellular processes.
Antibody Name:
XKR4 Antibody (PACO20940)
Antibody SKU:
PACO20940
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:20-1:100
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthetic peptide of human XKR4
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO20940(XKR4 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
XKR4 (XK-related protein 4) is a 650 amino acid, multi-pass membrane protein that likely is a component of the XK/Kell complex of the Kell blood group system. The gene encoding XKR4 maps to human chromosome 8, which is made up of nearly 146 million bases and encodes about 800 genes. Single nucleotide polymorphisms (SNPs) of the XKR4 gene are associated with iloperidone efficacy, a antipsychotic drug that is used to treat schizophrenic patients.
Synonyms:
XK, Kell blood group complex subunit-related family, member 4
UniProt Protein Function:
XKR4: Belongs to the XK family.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 8q12.1Cellular Component: membrane
