The XKR7 Polyclonal Antibody (PAC020938) is a valuable tool for researchers studying XKR7, a protein involved in various cellular processes, including cell migration and apoptosis. This antibody, generated in rabbits, has high specificity for human samples and has been validated for use in Western blot applications. By targeting the XKR7 protein, this antibody allows for the detection and analysis of XKR7 expression in different cell types, making it an essential tool for studies in cell biology and cancer research.XKR7, also known as Xenotropic and Polytropic Retrovirus Receptor 2, plays a crucial role in regulating cell function and survival.
Its involvement in processes such as apoptosis and cell movement makes it a potential target for investigating diseases like cancer and neurological disorders. Understanding the function of XKR7 can provide insights into disease mechanisms and potentially lead to the development of new therapeutic strategies targeting this protein. Whether studying cell behavior or disease pathways, the XKR7 Polyclonal Antibody is a versatile tool for researchers looking to explore the functions of XKR7 in various contexts.
Antibody Name:
XKR7 Antibody (PACO20938)
Antibody SKU:
PACO20938
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthetic peptide of human XKR7
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO20938(XKR7 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20938(XKR7 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
XKR7 (XK-related protein 7) is a 579 amino acid, multi-pass membrane protein that likely is a component of the XK/Kell complex of the Kell blood group system. The gene encoding XKR7 maps to human chromosome 20, which comprises approximately 2% of the human genome. Chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome.
Synonyms:
XK, Kell blood group complex subunit-related family, member 7
UniProt Protein Function:
XKR7: Belongs to the XK family.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 20q11.21Cellular Component: integral to membrane
