The Xkrx Antibody (PAC020941) is a polyclonal antibody specifically designed for researchers studying Xkrx, a key transcription factor involved in the regulation of genes related to cell differentiation and development. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications, including Western blotting.Xkrx, also known as Xenopus homolog of Krüppel-like factor 6, plays a critical role in the control of gene expression patterns that drive cell fate determination and tissue morphogenesis. Its involvement in these fundamental cellular processes makes it a valuable target for studies in developmental biology, stem cell research, and regenerative medicine.
By targeting the Xkrx protein, this antibody enables researchers to detect and analyze its expression in different cell types, providing insights into its function and regulatory mechanisms. Understanding the role of Xkrx is essential for unraveling the complex pathways underlying cell differentiation and tissue development, paving the way for innovative therapeutic interventions in various fields of biomedical research.
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO20941(XKRX Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200).
Gel: 8%SDS-PAGE, Lysate: 40 µg, Lane 1-3: Human normal stomach tissue, human liver cancer and thyroid cancer tissue, Primary antibody: PACO20941(XKRX Antibody) at dilution 1/400 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes.
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO20941(XKRX Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
This gene encodes a protein that is related to a component of the XK/Kell complex of the Kell blood group system. The encoded protein includes several transmembrane domains, is known to be exposed to the cell surface, and may function as a membrane transporter.
Synonyms:
XK, Kell blood group complex subunit-related, X-linked
UniProt Protein Function:
XKRX: a protein that is related to a component of the XK/Kell complex of the Kell blood group system. The encoded protein includes several transmembrane domains, is known to be exposed to the cell surface, and may function as a membrane transporter. [provided by RefSeq, May 2010]Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: Xq22.1
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein that is related to a component of the XK/Kell complex of the Kell blood group system. The encoded protein includes several transmembrane domains, is known to be exposed to the cell surface, and may function as a membrane transporter. [provided by RefSeq, May 2010]
