The YME1L1 Antibody (CAB10402) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the YME1L1 protein, this antibody enables the detection and analysis of YME1L1 in various cellular contexts, making it suitable for investigations in mitochondrial biology and related areas of research.YME1L1 is a critical component of the mitochondrial proteolytic system, playing a key role in maintaining mitochondrial function and cellular metabolism.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
YME1L1 Antibody
SKU:
CAB10402
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
FTSH, MEG4, PAMP, OPA11, YME1L, YME1L1
Positive Sample:
Mouse skeletal muscle, Mouse heart
Cellular Localization:
Mitochondrion Inner Membrane.
Calculated MW:
86kDa
Observed MW:
65kDa
The protein encoded by this gene is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method
Affinity purification
Gene ID
10730
RRID
AB_2757951
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates, using YME1L1 Rabbit pAb (CAB10402) at 1:2000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
