The ZADH2 Polyclonal Antibody (PACO01714) is a valuable tool for researchers studying ZADH2, a key enzyme involved in metabolic pathways and energy production. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the ZADH2 protein, this antibody allows for the detection and analysis of ZADH2 levels in various cell types, making it an essential tool for studies in metabolism, biochemistry, and cancer research.ZADH2, also known as zinc binding alcohol dehydrogenase domain containing 2, plays a critical role in cellular metabolism by catalyzing the conversion of alcohols to aldehydes.
Dysregulation of ZADH2 has been implicated in various diseases, including metabolic disorders and cancer. Understanding the function and expression of ZADH2 is essential for unraveling its role in these pathologies and developing targeted therapies to treat them.Overall, the ZADH2 Polyclonal Antibody is a reliable reagent for researchers investigating the molecular mechanisms underlying cellular metabolism and its implications for human health. Its specificity and sensitivity make it a valuable tool for exploring the role of ZADH2 in disease progression and identifying potential therapeutic targets.
Antibody Name:
ZADH2 Antibody
Antibody SKU:
PACO01714
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:
Human, Mouse, Rat
Immunogen:
synthesized peptide derived from the Internal region of human ZADH2.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
ZADH2; Zinc-binding alcohol dehydrogenase domain-containing protein 2
UniProt Protein Function:
Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest efficienty towards 15-keto-PGE2-alpha. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation.
