The ZC3HAV1 Polyclonal Antibody (CAB9219) is a valuable tool for researchers studying ZC3HAV1, a protein involved in antiviral immune responses. This antibody, produced in rabbits, has high specificity towards human samples and has been validated for use in Western blotting applications. By binding to the ZC3HAV1 protein, this antibody enables the detection and analysis of ZC3HAV1 in various cell types, making it an essential component for studies in virology and immune response mechanisms.
ZC3HAV1, also known as zinc finger CCCH-type antiviral protein 1, is a key player in the cellular response to viral infections. It functions by inhibiting the replication of certain viruses, thus highlighting its potential as a therapeutic target for antiviral drug development. Research into ZC3HAV1 is crucial for understanding the molecular mechanisms behind viral infections and host immune responses, with implications for the development of novel antiviral strategies.
Product Name:
ZC3HAV1 Rabbit Polyclonal Antibody
SKU:
CAB9219
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 150-400 of human ZC3HAV1 (NP_078901.3).
This gene encodes a CCCH-type zinc finger protein. This antiviral protein inhibits viral replication by recruiting cellular RNA degradation machineries to degrade viral mRNAs. The encoded protein plays an important role in the innate immune response against multiple DNA and RNA viruses, including Ebola virus, HIV and SARS-CoV-2 (which causes COVID-19).
Purification Method:
Affinity purification
Gene ID:
56829
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ZC3HAV1 Rabbit pAb (CAB9219) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
