The ZFAND2A Polyclonal Antibody (PAC020944) is a valuable tool for researchers studying the ZFAND2A protein, a zinc finger AN1-type domain-containing protein with a role in gene regulation and cellular signaling. This antibody, generated in rabbits, is highly specific for human samples and is validated for use in Western blot applications. By binding to the ZFAND2A protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in molecular biology and cellular signaling pathways.
ZFAND2A is a key player in gene expression regulation and has been implicated in various cellular processes, including development, differentiation, and disease pathogenesis. Its involvement in gene transcription and signal transduction pathways makes it a promising target for research into cancer, developmental disorders, and neurodegenerative diseases. Understanding the functions and mechanisms of ZFAND2A is essential for unraveling its role in cellular processes and identifying potential therapeutic interventions for related conditions.
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO20944(ZFAND2A Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
Gel: 12%SDS-PAGE, Lysate: 40 µg, Lane: Human normal kidney tissue, Primary antibody: PACO20944(ZFAND2A Antibody) at dilution 1/300 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes.
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20944(ZFAND2A Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
ZFAND2A (AN1-type zinc finger protein 2A) is a 171 amino acid, protein containing two AN1-type zinc fingers. AN1-type zinc fingers contain six conserved cysteines, two histidines and have a dimetal (zinc)-bound alpha/β fold. The gene encoding ZFAND2A maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome.
