The ZFAND2A Polyclonal Antibody (PAC020945) is a valuable tool for researchers studying ZFAND2A, a protein involved in various cellular processes including immune regulation and inflammation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blotting applications. By targeting the ZFAND2A protein, researchers can detect and analyze its presence in different cell types, making it an ideal choice for studies in immunology and cancer research.
ZFAND2A, also known as a zinc finger AN1-type containing 2A protein, plays a crucial role in modulating immune responses and inflammatory pathways. Its involvement in these processes makes it a promising target for research aimed at understanding diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. By investigating the functions of ZFAND2A, scientists can uncover new insights that may lead to the development of innovative therapies targeting immune-related diseases.
Antibody Name:
ZFAND2A Antibody (PACO20945)
Antibody SKU:
PACO20945
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human ZFAND2A
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO20945(ZFAND2A Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20945(ZFAND2A Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
ZFAND2A (AN1-type zinc finger protein 2A) is a 171 amino acid, protein containing two AN1-type zinc fingers. AN1-type zinc fingers contain six conserved cysteines, two histidines and have a dimetal (zinc)-bound alpha/β fold. The gene encoding ZFAND2A maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
