The ZFP36 Polyclonal Antibody is a valuable tool for researchers studying the protein ZFP36, which plays a key role in regulating gene expression and mRNA stability. This antibody, generated in rabbits, is highly specific to ZFP36 and is validated for use in Western blot applications, enabling accurate detection and analysis of ZFP36 in various cell types.ZFP36, also known as tristetraprolin (TTP), is involved in the post-transcriptional regulation of inflammatory genes and has been implicated in a variety of biological processes, including immune response and cell proliferation. Research on ZFP36 is essential for understanding how gene expression is controlled in different cellular contexts, making this antibody a valuable asset for studies in immunology, cancer research, and beyond.
By utilizing the ZFP36 Polyclonal Antibody, researchers can gain valuable insights into the molecular mechanisms underlying gene regulation and potentially identify new therapeutic targets for diseases characterized by dysregulated gene expression. This antibody is a reliable tool for investigating the functions of ZFP36 and its role in various physiological and pathological processes.
Product Name:
ZFP36 Polyclonal Antibody
SKU:
CAB1878
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 230-326 of human ZFP36 (NP_003398.3).
Enables several functions, including 14-3-3 protein binding activity; heat shock protein binding activity; and mRNA 3'-UTR AU-rich region binding activity. Involved in several processes, including cellular response to cytokine stimulus; cellular response to growth factor stimulus; and regulation of gene expression. Acts upstream of or within mRNA catabolic process. Located in cytoplasmic ribonucleoprotein granule; cytosol; and nucleus. Part of ribonucleoprotein complex. Colocalizes with RISC-loading complex.
Purification Method:
Affinity purification
Gene ID:
7538
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using ZFP36 Rabbit pAb (CAB1878) at 1:500 dilution incubated overnight at 4℃.Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L)(CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020)Exposure time: 180 s.
