The ZMYND10 Polyclonal Antibody (PAC01312) is a valuable tool for researchers studying the ZMYND10 protein, a key player in gene regulation and chromatin remodeling. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.ZMYND10, also known as Zinc finger MYND domain-containing protein 10, is involved in various cellular processes, including transcriptional regulation and epigenetic modifications. Its role in controlling gene expression makes it a compelling target for investigation in fields like cancer research, developmental biology, and stem cell research.
By detecting and analyzing ZMYND10 protein levels in different cell types, this antibody enables researchers to explore the functions and interactions of ZMYND10 in diverse biological contexts. Its versatility and specificity make it a valuable tool for advancing our understanding of gene regulation mechanisms and their implications in human health and disease.
ZMYND10: 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 3p21.3Cellular Component: cytoplasmMolecular Function: protein bindingDisease: Ciliary Dyskinesia, Primary, 22
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein containing a MYND-type zinc finger domain that likely functions in assembly of the dynein motor. Mutations in this gene can cause primary ciliary dyskinesia. This gene is also considered a tumor suppressor gene and is often mutated, deleted, or hypermethylated and silenced in cancer cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
