The ZNF18 Polyclonal Antibody (PAC021736) is a valuable tool for researchers studying ZNF18, a zinc finger protein known for its role in transcriptional regulation and gene expression. This antibody, raised in rabbits, has been optimized for use in various applications, including Western blot and immunohistochemistry.ZNF18 is a transcription factor that plays a key role in controlling the expression of target genes involved in various biological processes, including development, differentiation, and cell proliferation.
Its dysregulation has been associated with certain diseases, making it a potential therapeutic target for drug development.This polyclonal antibody specifically targets ZNF18, allowing researchers to detect and analyze its expression in different cell types and tissues. By understanding the function and regulation of ZNF18, researchers can gain insights into its role in disease progression and potentially identify new therapeutic strategies.
Antibody Name:
ZNF18 Antibody (PACO21736)
Antibody SKU:
PACO21736
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthesized peptide derived from internal of human ZNF18.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Thiesen HJ., New Biol. 2:363-374(1990).
Clonality:
Polyclonal
Conjugate:
Non-conjugated
Western blot analysis of extracts from HeLa cells, using ZNF18 antibody.
Synonyms:
Zinc finger protein 18; Zinc finger protein KOX11; Heart development-specific gene 1 protein; Zinc finger protein with KRAB and SCAN domains 6; ZNF18
UniProt Protein Function:
ZNF18: May be involved in transcriptional regulation. Belongs to the krueppel C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: DNA-binding; C2H2-type zinc finger proteinChromosomal Location of Human Ortholog: 17p11.2Cellular Component: nucleusMolecular Function: DNA binding; metal ion bindingBiological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter
zinc finger protein 18; zinc finger protein 535; zinc finger protein KOX11; zinc finger protein 18 (KOX 11); heart development-specific protein; heart development-specific gene 1 protein; zinc finger protein with KRAB and SCAN domains 6
UniProt Protein Name:
Zinc finger protein 18
UniProt Synonym Protein Names:
Heart development-specific gene 1 protein; Zinc finger protein 535; Zinc finger protein KOX11; Zinc finger protein with KRAB and SCAN domains 6
