Description
ZNF488 Antibody (PACO31336)
The ZNF488 Polyclonal Antibody (PAC031336) is a vital tool for research involving ZNF488, a zinc finger protein involved in gene regulation and transcriptional control. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it a reliable tool for experiments in various research fields.ZNF488, also known as a transcription factor, plays a crucial role in regulating gene expression and controlling cellular processes. Its involvement in cell differentiation and development makes it an intriguing target for studying various diseases, including cancer, neurodegenerative disorders, and developmental abnormalities.
By targeting ZNF488, researchers can gain valuable insights into the molecular mechanisms underlying these conditions and potentially develop novel therapeutic strategies.The ZNF488 Polyclonal Antibody can be used in a range of applications, including Western blotting, immunohistochemistry, and immunofluorescence, allowing for detailed analysis of ZNF488 expression and localization in different cell types and tissues. Its versatility and reliability make it an essential tool for advancing research in molecular biology, genetics, and disease pathology.
| Antibody Name: | ZNF488 Antibody (PACO31336) |
| Antibody SKU: | PACO31336 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Zinc finger protein 488 protein (1-200AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot Positive WB detected in: A549 whole cell lysate All lanes: ZNF488 antibody at 3.4µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 37, 26 kDa Observed band size: 37 kDa . |
 | Immunofluorescence staining of A549 cells with PACO31336 at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Immunohistochemistry of paraffin-embedded human brain tissue using PACO31336 at dilution of 1:100. |
| Background: | May be involved in transcriptional regulation. |
| Synonyms: | Zinc finger protein 488, ZNF488 |
| UniProt Protein Function: | ZNF488: May be involved in transcriptional regulation. Belongs to the krueppel C2H2-type zinc-finger protein family.Protein type: C2H2-type zinc finger proteinChromosomal Location of Human Ortholog: 10q11.22Molecular Function: protein bindingBiological Process: oligodendrocyte development |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q96MN9 |
| NCBI GenInfo Identifier: | 68566223 |
| NCBI Gene ID: | 118738 |
| NCBI Accession: | Q96MN9.1 |
| UniProt Secondary Accession: | Q96MN9,Q05CE0 |
| UniProt Related Accession: | Q96MN9 |
| Molecular Weight: | 25,670 Da |
| NCBI Full Name: | Zinc finger protein 488 |
| NCBI Synonym Full Names: | zinc finger protein 488 |
| NCBI Official Symbol: | ZNF488Â Â |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | zinc finger protein 488 |
| UniProt Protein Name: | Zinc finger protein 488 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Zinc finger protein |
| UniProt Gene Name: | ZNF488Â Â |
| UniProt Entry Name: | ZN488_HUMAN |
