The ZNF596 Polyclonal Antibody (PAC023269) is a valuable tool for researchers studying ZNF596, a key transcription factor involved in gene regulation and cellular processes. This antibody, generated in rabbits, exhibits high specificity towards ZNF596 in human samples and has been validated for use in Western blotting applications. By binding to the ZNF596 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it ideal for studies in molecular biology and genetics.ZNF596 is known to play a crucial role in the control of gene expression, particularly in the regulation of transcriptional activation and repression.
Its involvement in cellular functions such as differentiation, proliferation, and apoptosis underscores its importance in various physiological and pathological processes. Research on ZNF596 is essential for gaining insights into molecular mechanisms underlying diseases like cancer, developmental disorders, and neurodegenerative conditions, with implications for the development of targeted therapies and diagnostics.
Synthesized peptide derived from internal of human ZNF596.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from Jurkat cells, using ZNF596 antibody.
Immunohistochemistry analysis of paraffin-embedded human brain tissue using ZNF596 antibody.
Background:
May be involved in transcriptional regulation.
Synonyms:
Zinc finger protein 596; ZNF596;
UniProt Protein Function:
ZNF596: May be involved in transcriptional regulation. Belongs to the krueppel C2H2-type zinc-finger protein family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:
Protein type:C2H2-type zinc finger protein; Transcription regulation
Chromosomal Location of Human Ortholog: 8p23.3
Cellular Component: nucleus
Molecular Function:DNA binding; metal ion binding
Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent
