The ZNF75D Polyclonal Antibody (PACO1733) is a vital tool for researchers studying ZNF75D, a transcription factor that plays a key role in gene regulation and cellular functions. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in immunohistochemistry and Western blotting applications. It binds specifically to the ZNF75D protein, allowing for accurate detection and analysis in various cell types, making it an invaluable asset for studies in molecular biology and genetics.
ZNF75D is involved in the regulation of gene expression and is known to interact with other proteins to modulate cellular processes. Research into ZNF75D can provide insights into various diseases and conditions, such as cancer, developmental disorders, and neurological diseases. By understanding the function and activity of ZNF75D, researchers can identify potential therapeutic targets and pathways for treatment in these disease contexts.
Antibody Name:
ZNF75D Antibody
Antibody SKU:
PACO01733
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human ZNF75.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
ZNF75D; ZNF75; ZNF82; Zinc finger protein 75D; Zinc finger protein 75; Zinc finger protein 82
UniProt Protein Function:
ZNF75D: May be involved in transcriptional regulation. Belongs to the krueppel C2H2-type zinc-finger protein family.Protein type: DNA-binding; C2H2-type zinc finger proteinChromosomal Location of Human Ortholog: Xq26.3Cellular Component: nucleusMolecular Function: sequence-specific DNA binding; transcription factor activity; zinc ion bindingBiological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein that likely functions as a transcription factor. The protein, which belongs to the ZNF75 family, includes an N-terminal SCAN domain, a KRAB box, and five C2H2-type zinc finger motifs. Another functional gene belonging to this family is located on chromosome 16, while pseudogenes have been identified on chromosomes 11 and 12. Alternative splicing results in multiple transcripts variants. [provided by RefSeq, Jun 2010]
