The 4-HNE Polyclonal Antibody is a vital tool for researchers studying oxidative stress and lipid peroxidation. 4-HNE, or 4-hydroxynonenal, is a highly reactive aldehyde generated during the peroxidation of omega-6 polyunsaturated fatty acids. Elevated levels of 4-HNE have been linked to various diseases including neurodegenerative disorders, cardiovascular diseases, and cancer.This antibody, raised in rabbits, exhibits high specificity and sensitivity for detecting 4-HNE protein adducts in human samples. It is suitable for use in Western blot applications, allowing for the precise detection and quantification of 4-HNE modifications in various cell types and tissues.
By targeting 4-HNE adducts, researchers can gain valuable insights into the mechanisms underlying oxidative stress-related pathologies and potentially identify novel therapeutic targets for mitigating the deleterious effects of lipid peroxidation. The 4-HNE Polyclonal Antibody is a valuable tool for advancing research in the fields of oxidative stress, lipid metabolism, and disease pathogenesis.
Product Name:
4-HNE Polyclonal Antibody
Product Code:
CAB24456
Reactivity:
Species independent
Applications:
Western blotting, Immunofluorescence
Host Species:
Rabbit
Purification Method:
Affinity purification
Isotype:
IgG
Reactivity:
Species independent
Tested Applications:
WB, IF/ICC, ELISA
Key Applications:
Western blotting, Immunofluorescence
Recommended Dilution:
WB 1:1000-1:5000, IF/ICC 1:50-1:200
Storage Buffer:
Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
