The A4GALT Polyclonal Antibody (CAB8817) is a valuable tool for researchers studying the A4GALT protein, which plays a crucial role in the synthesis of the A4GALT antigen. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.By binding to the A4GALT protein, this antibody allows for the detection and analysis of A4GALT in various cell types, making it an ideal choice for studies in glycobiology and cancer research. The A4GALT antigen has been implicated in tumor progression and metastasis, highlighting the importance of investigating its functions in cancer development.
Further research on the A4GALT protein could lead to a greater understanding of its role in glycosylation processes and its potential as a therapeutic target for cancer treatment. By utilizing the A4GALT Polyclonal Antibody, scientists can gain valuable insights into the mechanisms underlying cancer progression and potentially identify new strategies for combating this deadly disease.
Product Name:
A4GALT Rabbit Polyclonal Antibody
SKU:
CAB8817
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 244-353 of human A4GALT (NP_059132.1).
Golgi apparatus membrane, Single-pass type II membrane protein.
Calculated MW:
40kDa
Observed MW:
45kDa
The protein encoded by this gene catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. This protein, a type II membrane protein found in the Golgi, is also required for the synthesis of the bacterial verotoxins receptor. Alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
53947
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using A4GALT antibody (CAB8817) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 20s.
