The ABI3BP Polyclonal Antibody (CAB14581) is specifically designed for research involving ABI3BP, a protein encoded by the ABI gene and implicated in various cellular processes. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. It binds to the ABI3BP protein, enabling accurate detection and analysis in a variety of cell types, making it an ideal tool for studies in molecular biology and cell signaling.ABI3BP, also known as ABI family member 3-binding protein, is involved in cell proliferation, migration, and adhesion, making it a key player in processes like embryonic development, tissue repair, and cancer progression.
Understanding the role of ABI3BP is crucial for unraveling its potential therapeutic implications in diseases like cancer, diabetes, and cardiovascular disorders. This antibody provides researchers with a valuable tool for investigating the function and regulation of ABI3BP in various biological contexts.
Product Name:
ABI3BP Rabbit Polyclonal Antibody
SKU:
CAB14581
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 29-280 of human ABI3BP (NP_056244.2).
Predicted to enable actin filament binding activity and glycosaminoglycan binding activity. Predicted to be involved in regulation of actin cytoskeleton reorganization; regulation of dendritic spine morphogenesis; and regulation of postsynaptic density assembly. Predicted to act upstream of or within extracellular matrix organization and positive regulation of cell-substrate adhesion. Located in extracellular space. Colocalizes with collagen-containing extracellular matrix.
Purification Method:
Affinity purification
Gene ID:
25890
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from U-87MG cells, using ABI3BP Rabbit pAb (CAB14581) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 20s.
