The Acad8 Antibody (PAC015247) offered by AssayGenie is a valuable tool for researching the role of Acad8, an enzyme involved in fatty acid metabolism and energy production in the mitochondria. This polyclonal antibody, generated in rabbits, exhibits high reactivity towards human samples and has been validated for use in Western blot applications.Acad8 is a key player in lipid metabolism and energy production, making it a promising target for studies related to metabolic disorders, obesity, and mitochondrial diseases.
By detecting and analyzing the Acad8 protein in various cell types, researchers can gain insights into its functions and potential implications in human health.With its specificity and reliability, the Acad8 Antibody is ideal for investigations in biochemistry, metabolism, and mitochondrial biology. By studying the role of Acad8, scientists can uncover new pathways and mechanisms that may lead to the development of therapeutic interventions for metabolic diseases and related conditions.
Antibody Name:
ACAD8 Antibody (PACO15247)
Antibody SKU:
PACO15247
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:2000, IHC:1:15-1:50
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Fusion protein of human ACAD8
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15247(ACAD8 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200).
Background:
This gene encodes a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acid, or branch chained amino acid, The encoded protein is a mitochondrial enzyme that functions in catabolism of the branched-chain amino acid, valine. Defects in this gene are the cause of isobutyryl-CoA dehydrogenase deficiency.
Synonyms:
acyl-CoA dehydrogenase family, member 8
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. The encoded protein is a mitochondrial enzyme that functions in catabolism of the branched-chain amino acid valine. Defects in this gene are the cause of isobutyryl-CoA dehydrogenase deficiency.[provided by RefSeq, Nov 2009]
