The ADORA3 Polyclonal Antibody (CAB18524) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, is highly specific and reacts with human samples, making it suitable for use in Western blot applications.ADORA3 is known to be involved in immune regulation, inflammation, and cardiovascular function, making it a promising target for research in immunology, cardiovascular biology, and drug development. By binding to the ADORA3 protein, this antibody enables the detection and analysis of ADORA3 expression in different cell types, providing valuable insights into its role in various biological processes.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.
Product Name:
ADORA3 Polyclonal Antibody
SKU:
CAB18524
Size:
20μL, 100μL
Reactivity:
Mouse, Rat
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
A3AR, ADORA3
Positive Sample:
Mouse testis, Rat testis
Cellular Localization:
Membrane, Multi-Pass Membrane Protein.
Calculated MW:
36kDa
Observed MW:
36kDa
This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Alternative splicing results in multiple transcript variants. This gene shares its 5' terminal exon with some transcripts from overlapping GeneID:57413, which encodes an immunoglobulin domain-containing protein.
Purification Method
Affinity purification
Gene ID
140
RRID
AB_2862288
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates, using ADORA3 Rabbit pAb (CAB18524) at 1:2000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
