The AKR1B10 Antibody (CAB7823) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By binding to the AKR1B10 protein, this antibody allows for detection and analysis in a variety of cell types, making it ideal for investigations in cancer biology and drug development.AKR1B10, also known as aldose reductase family 1 member B, is involved in cellular detoxification processes and plays a role in metabolizing lipid peroxidation products.
This antibody is validated for use in WB, IP, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
AKR1B10 Antibody
SKU:
CAB7823
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
293T, Mouse small intestine, Mouse stomach, Mouse liver, Mouse kidney, Rat small intestine
Cellular Localization:
Lysosome, Secreted.
Calculated MW:
36kDa
Observed MW:
36kDa
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis.
Purification Method
Affinity purification
Gene ID
57016
RRID
AB_2768305
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using AKR1B10 Rabbit pAb (CAB7823) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
