The ANKRD49 Polyclonal Antibody (PAC038634) is a valuable tool for researchers studying ANKRD49, a protein involved in various biological processes, including cell signaling and gene expression regulation. This antibody, generated in rabbits, exhibits high reactivity towards human samples and has been validated for use in Western blot applications. By specifically binding to the ANKRD49 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an essential component for studies in molecular biology and cell signaling pathways.
ANKRD49 is a multifunctional protein that plays a crucial role in regulating cellular processes, such as cell growth, differentiation, and apoptosis. Its involvement in these pathways highlights its significance in diseases like cancer, cardiovascular disorders, and neurological conditions. Investigating the function of ANKRD49 is vital for uncovering its potential as a therapeutic target for these diseases and developing targeted treatments that can modulate its activity for clinical benefits.
Western Blot. Positive WB detected in: HEK293 whole cell lysate. All lanes: ANKRD49 antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 28 kDa. Observed band size: 28 kDa.
Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO38634 at dilution of 1:100.
Background:
Induces HBG1 expression. May have a role in spermatogenesis where it promotes autophagy in response to serum starvation, via the NF-kappaB pathway.
Synonyms:
Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor), ANKRD49, FGIF
UniProt Protein Function:
ANKRD49: Chromosomal Location of Human Ortholog: 11q21Cellular Component: nucleusMolecular Function: protein bindingBiological Process: positive regulation of transcription, DNA-dependent
