The Annexin A4/Annexin IV Antibody (CAB6280) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blotting applications. By binding specifically to Annexin A4, this antibody enables precise detection and analysis of the protein in various cell types, making it an essential component for studies in cell biology and neuroscience.Annexin A4 is known for its role in regulating membrane fusion events and vesicle trafficking, making it a crucial player in cellular processes such as neurotransmitter release and cell signaling.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
Annexin A4/Annexin IV Antibody
SKU:
CAB6280
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Cell Surface, Cytoplasm, Cytoplasmic Vesicle, Extracellular Exosome, Nuclear Membrane, Nucleus, Perinuclear Region Of Cytoplasm, Plasma Membrane.
Calculated MW:
36kDa
Observed MW:
35kDa
Annexin IV (ANX4) belongs to the annexin family of calcium-dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. ANX4 has 45 to 59% identity with other members of its family and shares a similar size and exon-intron organization. Isolated from human placenta, ANX4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANX4 is almost exclusively expressed in epithelial cells. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method
Affinity purification
Gene ID
307
RRID
AB_2766885
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using Annexin A4/Annexin IV Rabbit pAb (CAB6280) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 60s.
