The Alcohol Dehydrogenase Monoclonal Antibody (CAB19624) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in various applications including Western blot and immunohistochemistry.Alcohol dehydrogenase plays a crucial role in the breakdown of alcohol into acetaldehyde, a toxic byproduct that can contribute to liver damage and other health issues. Studying the expression and activity of alcohol dehydrogenase is important for understanding alcohol metabolism, alcohol-related diseases, and potential treatment options.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse samples.
Product Name:
Alcohol Dehydrogenase Monoclonal Antibody
SKU:
CAB19624
Size:
20μL, 100μL
Reactivity:
Mouse
Clone Number:
ARC2203
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
ADH1, Alcohol Dehydrogenase
Positive Sample:
Mouse lung
Cellular Localization:
Cytosol, Nucleoplasm, Plasma Membrane.
Calculated MW:
40kDa
Observed MW:
40kDa
This gene encodes a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze the oxidation of alcohols to aldehydes. This gene is active in the liver in early fetal life but only weakly active in adult liver. This gene is found in a cluster with six additional alcohol dehydrogenase genes, including those encoding the beta and gamma subunits, on the long arm of chromosome 4. Mutations in this gene may contribute to variation in certain personality traits and substance dependence. [provided by RefSeq, Nov 2010]
Purification Method
Affinity purification
Gene ID
124
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from Mouse lung, using Alcohol Dehydrogenase Rabbit mAb (CAB19624) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
