The BMP4 Monoclonal Antibody (CAB21065) is a high-quality antibody developed for reliable detection and analysis of target proteins. Raised in rabbits, this antibody is highly specific and reactive with human samples, making it ideal for use in Western blotting and immunohistochemistry applications.BMP4 plays a key role in skeletal and neural development, making it a target of interest in studies related to bone formation, cartilage development, and neural patterning. By detecting and analyzing BMP4 expression in different cell types and tissues, researchers can gain insights into its function and signaling pathways, paving the way for new therapeutic approaches in regenerative medicine, musculoskeletal disorders, and neurodevelopmental diseases.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
BMP4 Monoclonal Antibody
SKU:
CAB21065
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC52124
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers.
Purification Method
Affinity purification
Gene ID
652
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates, using BMP4 Rabbit mAb (CAB21065) at1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Negative control (NC): U-937 Exposure time: 90s.
Western blot analysis of lysates from Rat lung, using BMP4 Rabbit mAb (CAB21065) at1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
