The HCAR1 Polyclonal Antibody (CAB20321) is specifically designed for researchers investigating HCAR1, a cell surface receptor known for its role in mediating the effects of lactate in the body. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in a variety of applications, including Western blotting. By binding to the HCAR1 protein, this antibody enables precise detection and analysis in different cell types, making it a valuable tool for studies in metabolism, immunology, and cancer research.
HCAR1, also known as GPR81, is an important player in metabolism and immune regulation, primarily responding to lactate levels to influence cellular functions. Its involvement in metabolic pathways and immune responses makes it a promising target for research in diseases related to metabolism dysfunction and immune dysregulation. By unraveling the mechanisms of HCAR1 activity, researchers can pave the way for developing novel therapies targeting metabolic disorders, inflammation, and cancer progression.
Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:
IgG
Sequence:
Email for sequence
Gene ID:
27198
Uniprot:
Q9BXC0
Calculated MW:
39kDa
Observed MW:
39KDa
Background:
G protein-coupled receptors (GPCRs, or GPRs), such as GPR81, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.
