The HSPA1B Monoclonal Antibody (CAB19317) is a valuable tool for researchers studying the heat shock protein A1B, a critical stress response protein involved in various cellular processes. This antibody, developed in mice, specifically targets the HSPA1B protein in human samples and is validated for use in techniques such as Western blot and immunohistochemistry.HSPA1B is a member of the heat shock protein family, known for its chaperone function in protein folding and stability during cellular stress. Research into HSPA1B has revealed its role in protecting cells from damage and promoting cell survival under adverse conditions.
Its involvement in diseases such as cancer, neurodegenerative disorders, and cardiovascular diseases highlights its potential as a therapeutic target.By using the HSPA1B Monoclonal Antibody, researchers can accurately detect and analyze the expression of HSPA1B in various cell types and tissues, providing insights into its function and potential as a biomarker or therapeutic target. This antibody is a valuable tool for studying the role of HSPA1B in cellular stress responses and disease pathogenesis.
Product Name:
HSPA1B Polyclonal Antibody
SKU:
CAB19317
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 557-641 of human HSPA1B (NP_005337.2).
This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.
Purification Method:
Affinity purification
Gene ID:
3304
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from MCF7 cells, using HSP70 Rabbit pAb (CAB19317) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
